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Owing to its high affinity for phosphorylated ubiquitin, Parkin is easily transported from the cytoplasm to the mitochondria

Recent research has identified the signaling pathway JAK-STAT as particularly involved, which has led to the development of JAK inhibitors (first specific treatment approved in 2022)

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Controls were treated with 1 PBS and showed 100% growth, while tests measured the percentage decrease in biofilm biomass with respect to this control

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